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The American Macular Degeneration Foundation recommends that people with Stargardt's or a history of the eye disease in close family members obtain genetic counseling before starting their own families.
Because vision loss often appears in young children with Stargardt's, low vision counseling from your eye doctor is essential to make sure that classroom learning is not hampered.
For example, a child with Stargardt's may need to use large print books and special devices that magnify print.
Phenotypic variation in a family with pseudodominant Stargardt disease. JAMA Ophthalmology. March [e-pub ahead of print].
Makindus receives orphan designation for MI for Stargardt's disease. June Accessed March ACT announces first Stargardt patient treated with higher dosage of embryonic stem cell-derived retinal pigment epithelial cells.
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Add files via upload. Apr 30, Fix cpu support. May 1, Initial commit. Dec 4, Apr 27, Jul 3, The other five percent of cases are caused by rarer mutations in different genes that play a role in lipofuscin function.
An eye care professional can make a positive diagnosis of Stargardt disease by examining the retina. Lipofuscin deposits can be seen as yellowish flecks in the macula.
The flecks are irregular in shape and usually extend outward from the macula in a ring-like pattern. Currently, there is no treatment for Stargardt disease.
Some ophthalmologists encourage people with Stargardt disease to wear dark glasses and hats when out in bright light to reduce the buildup of lipofuscin.
Cigarette smoking and second hand smoke should be avoided. Animal studies suggest that high-dose vitamin A may increase lipofuscin accumulation and potentially accelerate vision loss.
A number of services and devices can help people with Stargardt disease carry out daily activities and maintain their independence. Because many people with Stargardt disease will become visually disabled by their 20s, the disease can have a significant emotional impact.
Work, socializing, driving and other activities that may have come easily in the past are likely to become challenging. Over the past several decades, researchers have identified hundreds of genes that contribute to inherited eye diseases, including Stargardt disease.
Many studies continue to explore the biology and genetics of Stargardt disease, and of macular degeneration more generally.
The main goals are to better understand the natural course of the disease, to make contact with people who may be interested in future clinical trials, and to collect blood, skin, and DNA samples from those people.
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